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First published on August 27, 2007, doi:10.1177/0363546507305455
This version was published on December 1, 2007
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Right arrow Chondral/cartilage
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The American Journal of Sports Medicine 35:2014-2021 (2007)
© 2007 American Orthopaedic Society for Sports Medicine

Arthroscopic Autologous Osteochondral Grafting for Cartilage Defects of the Knee

Prospective Study Results at a Minimum 7-Year Follow-up

Maurilio Marcacci, MD, Elizaveta Kon, MD*, Marco Delcogliano, MD, Giuseppe Filardo, MD, Maurizio Busacca, MD and Stefano Zaffagnini, MD

From the Rizzoli Orthopedic Institute, Bologna, Italy

* Address correspondence to Elizaveta Kon, MD, Laboratorio di Biomeccanica, Istituti Ortopedici Rizzoli, Via Di Barbiano, 1/10, 40136, Bologna, Italy (e-mail: e.kon{at}biomec.ior.it).

Background: Articular cartilage lesions, with their inherent limited healing potential, remain a challenging problem for orthopaedic surgeons. Various approaches have been proposed to treat these lesions; nevertheless, opinions on indications and clinical efficacy of these techniques are still controversial.

Purpose: To evaluate the outcome of osteochondral autografts for treatment of femoral condyle cartilage lesions at a medium-to long-term follow-up.

Study Design: Case series; Level of evidence, 4.

Methods: We prospectively evaluated 30 patients (mean age, 29.3 years) with full-thickness knee chondral lesions (<2.5 cm2) treated with arthroscopic autologous osteochondral transplantation. Thirteen patients underwent previous surgery, while 17 patients were operated on for the first time. In 19 patients, associated procedures were performed. All patients were evaluated at 2- and 7-year follow-up. The International Cartilage Repair Society form, Tegner score, and magnetic resonance imaging were used for clinical evaluation.

Results: The International Cartilage Repair Society objective evaluation showed 76.7% of patients had good or excellent results at 7-year follow-up, and International Knee Documentation Committee subjective score significantly improved from preoperative (34.8) to 7-year follow-up (71.8). The Tegner evaluation showed a significant improvement after the surgery at 2- and 7-year follow-up (from 2.9 to 6.2 and 5.6, respectively); however, we noticed reduced sports activity from 2- to 7-year follow-up. Magnetic resonance imaging evaluation showed good integration of the graft in the host bone and complete maintenance of the grafted cartilage in more than 60% of cases.

Conclusion: The results of this technique at medium- to long-term follow-up are encouraging. This arthroscopic 1-step surgery appears to be a valid solution for treatment of small, grade III to IV cartilage defects.

Key Words: cartilage repair • osteochondral autografting • mosaicplasty • chondral defect • chondromalacia • knee • arthroscopy







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