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First published on January 25, 2006, doi:10.1177/0363546505281918
This version was published on June 1, 2006
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The American Journal of Sports Medicine 34:1020-1038 (2006)
© 2006 American Orthopaedic Society for Sports Medicine

Clinical Sports Medicine Update

Autologous Chondrocyte Implantation Postoperative Care and Rehabilitation

Science and Practice

Karen Hambly, PT, MCSP*,{dagger}, Vladimir Bobic, MD, FRCSEd{ddagger}, Barbara Wondrasch, PT§, Dieter Van Assche, PT, MScll and Stefan Marlovits, MD, MBA

From the {dagger} Department of Health and Human Sciences, London Metropolitan University, London, United Kingdom, {ddagger} Chester Knee Clinic, The Grosvenor Nuffield Hospital, Chester, United Kingdom, the § Academy for Physiotherapy of the General Hospital of Vienna, Vienna, Austria, the || Department of Rheumatology, University Hospital Leuven, Leuven, Belgium, and the Department of Traumatology, Medical University of Vienna, Vienna, Austria

* Address correspondence to Karen Hambly, Department of Health and Sciences, 166–220 Holloway Road, London, UK N7 8DB (e-mail: k.hambly{at}londonmet.ac.uk).

Autologous chondrocyte implantation is an advanced, cell-based orthobiological technology used for the treatment of chondral defects of the knee. It has been in clinical use since 1987 and has been performed on 12 000 patients internationally; but despite having been in clinical use for more than 15 years, the evidence base for rehabilitation after autologous chondrocyte implantation is notably deficient. The authors review current clinical practice and present an overview of the principles behind autologous chondrocyte implantation rehabilitation practices. They examine the main rehabilitation components and discuss their practical applications within the overall treatment program, with the aim of facilitating the formulation of appropriate, individualized patient rehabilitation protocols for autologous chondrocyte implantation.

Key Words: rehabilitation • cartilage repair • autologous chondrocyte implantation (ACI) • knee • patellofemoral • tibiofemoral




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