| HOME | HELP | CONTACT US | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Sign In to gain access to subscriptions and/or personal tools.
|
|
|
|||||||
Sign In to gain access to subscriptions and/or personal tools. |
|||||||||
Orthopaedic Bioengineering Laboratory, San Diego Veterans Administration Medical Center, Malcolm and Dorothy Coutts Institute for Joint Reconstruction and Research, and the University of California, San Diego, LaJolla, California
Orthopaedic Bioengineering Laboratory, San Diego Veterans Administration Medical Center, Malcolm and Dorothy Coutts Institute for Joint Reconstruction and Research, and the University of California, San Diego, LaJolla, California
Orthopaedic Bioengineering Laboratory, San Diego Veterans Administration Medical Center, Malcolm and Dorothy Coutts Institute for Joint Reconstruction and Research, and the University of California, San Diego, LaJolla, California
Orthopaedic Bioengineering Laboratory, San Diego Veterans Administration Medical Center, Malcolm and Dorothy Coutts Institute for Joint Reconstruction and Research, and the University of California, San Diego, LaJolla, California
In order to assess the healing of the medial collateral ligament (MCL) and to detect the various effects of treatment regimens, in vivo animal experiments using a canine model were performed. Thirty-five canine MCLs were surgically transected and treated using three clinically popular regimens, e.g., no repair with cage and farm activities (Group 1), repair with 3 weeks immobilization (Group 2), and repair with 6 weeks im mobilization (Group 3). The varus-valgus laxity of the knee joint, structural properties of the femur-MCL-tibia (FMT) complex and the mechanical properties of the MCL substance (healing site) were quantitatively meas ured at 6, 12, and 48 weeks postoperatively. It was found that Group 1 animals had the best results. The varus-valgus laxity of the knee joint and the structural properties of the FMT complex returned to values comparable with the contralateral control by 12 weeks. The recovery of the mechanical properties of the MCL substance was slower and not complete, even at 48 weeks. In confirmation with previous studies, prolonged immobilization was shown to have deleterious effects on MCL healing. The results of this study indicated that early mobilization is the treatment of choice in cases of isolated MCL injury. Also, this study emphasized the importance and effectiveness of using various biome chanical parameters in addition to the conventional ultimate values at failure to evaluate the progress of soft tissue repair.
This article has been cited by other articles:
|
|
 |
|
  K. T. Jensen, D. P. Rabago, T. M. Best, J. J. Patterson, and R. Vanderby Jr Response of Knee Ligaments to Prolotherapy in a Rat Injury Model Am. J. Sports Med., July 1, 2008; 36(7): 1347 - 1357. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Tei, T. Matsumoto, Y. Mifune, K. Ishida, K. Sasaki, T. Shoji, S. Kubo, A. Kawamoto, T. Asahara, M. Kurosaka, et al. Administrations of Peripheral Blood CD34-Positive Cells Contribute to Medial Collateral Ligament Healing via Vasculogenesis Stem Cells, March 1, 2008; 26(3): 819 - 830. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. F. LaPrade, F. A. Wentorf, E. J. Olson, and C. S. Carlson An In Vivo Injury Model of Posterolateral Knee Instability Am. J. Sports Med., August 1, 2006; 34(8): 1313 - 1321. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Yoshiya, R. Kuroda, K. Mizuno, T. Yamamoto, and M. Kurosaka Medial Collateral Ligament Reconstruction Using Autogenous Hamstring Tendons: Technique and Results in Initial Cases Am. J. Sports Med., September 1, 2005; 33(9): 1380 - 1385. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. A. Hanson, P. S. Weinhold, H. M. Afshari, and L. E. Dahners The Effect of Analgesic Agents on the Healing Rat Medial Collateral Ligament Am. J. Sports Med., May 1, 2005; 33(5): 674 - 679. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Nakamura, S. Horibe, Y. Toritsuka, T. Mitsuoka, H. Yoshikawa, and K. Shino Acute Grade III Medial Collateral Ligament Injury of the Knee Associated with Anterior Cruciate Ligament Tear: The Usefulness of Magnetic Resonance Imaging in Determining a Treatment Regimen Am. J. Sports Med., March 1, 2003; 31(2): 261 - 267. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. P. Provenzano, D. A. Martinez, R. E. Grindeland, K. W. Dwyer, J. Turner, A. C. Vailas, and R. Vanderby Jr. Hindlimb unloading alters ligament healing J Appl Physiol, January 1, 2003; 94(1): 314 - 324. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. A. Hildebrand, S. L-Y. Woo, D. W. Smith, C. R. Allen, M. Deie, B. J. Taylor, and C. C. Schmidt The Effects of Platelet-Derived Growth Factor-BB on Healing of the Rabbit Medial Collateral Ligament: An In Vivo Study Am. J. Sports Med., July 1, 1998; 26(4): 549 - 554. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Aglietti, R. Buzzi, P. P. M. Menchetti, and F. Giron Arthroscopically Assisted Semitendinosus and Gracilis Tendon Graft in Reconstruction for Acute Anterior Cruciate Ligament Injuries in Athletes Am. J. Sports Med., December 1, 1996; 24(6): 726 - 731. [Abstract] [PDF]
|
|
|
|
|
|
G. Y. F. Ng, B. W. Oakes, l. D. McLean, O. W. Deacon, and D. Lampard The Long-Term Biomechanical and Viscoelastic Performance of Repairing Anterior Cruciate Ligament after Hemitransection Injury in a Goat Model Am. J. Sports Med., January 1, 1996; 24(1): 109 - 117. [Abstract] [PDF]
|
|
|
|
|
|
L. Durselen, L. Claes, and H. Kiefer The Influence of Muscle Forces and External Loads on Cruciate Ligament Strain Am. J. Sports Med., January 1, 1995; 23(1): 129 - 136. [Abstract] [PDF]
|
|
|
|
|
|
B. Reider, M. R. Sathy, J. Talkington, N. Blyznak, and S. Kollias Treatment of Isolated Medial Collateral Ligament Injuries in Athletes with Early Functional Rehabilitation: A Five-year Follow-up Study Am. J. Sports Med., July 1, 1994; 22(4): 470 - 477. [Abstract] [PDF]
|
|
|
|
|
|
A. J. Robins, A. P. Newman, and R. T. Burks Postoperative return of motion in anterior cruciate ligament and medial collateral ligament injuires: The effect of medial collateral ligament rupture location Am. J. Sports Med., January 1, 1993; 21(1): 20 - 25. [Abstract] [PDF]
|
|
|
|
|
|
C. T. Lechner and L. E. Dahners Healing of the medial collateral ligament in unstable rat knees Am. J. Sports Med., September 1, 1991; 19(5): 508 - 512. [Abstract] [PDF]
|
|
|
|
|
|
P. Burroughs and L. E. Dahners The effect of enforced exercise on the healing of ligament injuries Am. J. Sports Med., July 1, 1990; 18(4): 376 - 378. [Abstract] [PDF]
|
|
| HOME | HELP | CONTACT US | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
