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The American Journal of Sports Medicine 11:379-389 (1983)
© 1983 SAGE Publications

Medial collateral ligament healing

A multidisciplinary assessment in rabbits

C. Frank, MD

Division of Orthopaedic Surgery, University of California, San Diego

S.L.-Y. Woo, PhD

Veterans Administration Medical Center, San Diego, California

D. Amiel, MS

Veterans Administration Medical Center, San Diego, California

F. Harwood

Veterans Administration Medical Center, San Diego, California

M. Gomez, MS

Veterans Administration Medical Center, San Diego, California

W. Akeson, MD

Veterans Administration Medical Center, San Diego, California

Medial collateral ligament healing without treatment has been studied in a rabbit model. Complete midsubstance gaps were found to heal by distinct scar formation over time. This healing process was fast since the gap was bridged quickly; however, more subtle changes in ap pearance of the healing tissue continued for many months. The ligament "scar" was found to be structur ally abnormal chemically and mechanically even at long- term followup. A plateau in its improvement suggests that the scar may never approach normal ligament characteristics (without treatment). A baseline of liga ment healing by scar formation has been established.




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